Intuniv for ADHD: Metabolic Challenges

by Dr Charles Parker on February 1, 2010 · 11 comments

Burn Rate Explained

Intuniv, As With Any ADHD Medications: Watch the Burn Rate

Intuniv Posts:
This post is the fifth, with four others, documenting Intuniv Overview, Dosing Details, Drug Interactions and Addiction Indications. Please review all of these posts and the many comments [over 150] on the Overview post to see what readers are saying about Intuniv, this interesting new ADHD non-stimulant medication.

Burn Rate:
If you have been reading CorePsych Blog you will note that I have been writing about my new book, – and the good news, it’s finished, and in edit at this moment – I do hope to get it out by March ‘10. The Patient’s Guide for ADHD Medications: What To Do When Nothing Is Working details an entire chapter on Burn Rate, as everyone who takes ADHD meds should absolutely master the burn rate principle.

This Specific Q & A:
- Is an example of the many Intuniv questions, challenges and positive remarks in these several posts:

Question About 8 yo Boy, Picky Eater and Metabolic Challenges:
“I have just stumbled across you and this site in my research into Intuniv. My son just recently turned 8 and was diagnosed with ADHD this past spring. As I continually read about ADHD kids Luke seems wise beyond his years, is very bright when it comes to building things, or math, and picks things up quickly when he is receiving instruction one on one or in a very small group,- but he struggles in school generally. Long story short, we started with a Central Auditory Processing Disorder diagnosis when he was six.  His primary issue seemed to be language, both receptive and expressive. An exam with an audiologist confirmed a fairly significant CAPD at the time. As he progressed in school it was obvious that ADHD was also a large part of his problems as impulsivity, restlessness, inability to attend, and defiance increased as he got older. We saw a neurologist who, after an EEG, prescribed Focalin XR. This worked like MAGIC, at first.

We started with 5mg and after about a month moved up to 10mg. He was able to focus, concentrate and made great strides in school. His language issues even seemed to improve. Now it seems the Focalin is either failing him or is the wrong drug. His ability to focus has tanked, he has become very impulsive (throwing things, slamming things on his desk) and is increasingly defiant (refuses to do work, follow directions). While other times he seems spaced out, and at home sometimes too compliant, and sometimes melancholy for no reason. With age it seems his receptive language abilities are about right, and at developmental level, but his expressive abilities are still below, which of course is leading to some frustration on his part especially when he is supposed to expressing himself through writing. We were seen by the NP in the neurologist’s office today and she suggested Intuniv. From what I’m reading it sounds like it may work for Luke but she has suggested we stay on the Focalin while we start the Intuniv? Do you agree? (She mentioned d/c’ing the Focalin eventually)

Second, in one of the posts above you mentioned something about “immune dysfunction, bowel challenges and is-he-a-picky-eater”. While Luke is rarely sick, I don’t think he has a solid BM in his life (not watery, but always very, very soft) and he would live on Mac and cheese, peanut butter and jelly and chips if I’d let him. He NEVER willingly tries anything new and is indeed very picky about what he eats. As all of this is very new to me can you shed some light on what this may have to do with anything and what to do about it – or point me to the best place to read about it? We have tried adjusting his diet, etc. in the past but because he is so picky it is very difficult to do.

An Additional Metabolic Point - Headaches
One additional thing that the NP this a.m. more or less ignored – prior to starting meds Luke would wake up in the middle of the night crying and saying his head hurt. He’d be up 30 min. or more, would eventually throw up and then go back to sleep. In the morning you’d never know anything happened. This would happen about once a month from the time he was about 6. I only recall it happening once during the day at school. Once we started Focalin those incidents ceased completely. We had our first return of that 2 nights ago. Any idea what that’s all about? Initially the neurologist said it was “interesting”but had little else to say about it.”

My Answer, Abbreviated To Stay With Metabolism and Burn Rate:
My reaction to this question and many others seen on the many comments on Intuniv and Vyvanse: We must always look at the metabolic hints, the possible changes in metabolic rate before starting the meds. They are subtle but include the following:
- History of bowel issues, too soft, too hard, constipation, diarrhea, monolithic stools, too slow in transit time,
- Developmental delay issues: CAPD, speech issues, Asperger’s, Autism,
- History of Fetal Alcohol exposure
- Headaches, stomach aches, tired all of the time, dark circles under the eyes, pale skin
- Picky Eater
- Not eating breakfast, waking with stomach issues and no appetite
- History of failure with many meds – including stimulants or non-stimulants [Intuniv, Strattera]
- Narrow Therapeutic Window
- History of food allergies even back to early childhood, e.g. “lactose intolerance”
- History of rashes, allergies, asthma, upper respiratory infections, ear infections

If we don’t look at these issues [and more] we cannot predict what the outcome with the medications will be – and every one of these issues can significantly change the underlying metabolic patterns, the amount of neurotransmitters in the body, and the cofactors that burn the neurotransmitters effectively.

Medication management now requires a full awareness of the entire pattern including nutrition [which feeds the amino acid building blocks for neurotransmitters and cofactors], – without more careful questioning at the outset we will have predictable problems – as the burn rate will vary dramatically with all of these variables. Burn rate will effect Duration of Effectiveness [DOE] – dosage patterns and speed of titration at the onset of meds.

Then, if Burn Rate varies, we must always take the next step to measure the immune dysregulations, the neurotransmitters, and the downstream endocrine issues so often found with these upstream irregularities.

Phone Consult Availability
Check out these remarks regarding how to start these reviews with a phone consult: See this post on Intuniv: Comment by Gina Pera on January 29, ‘10 2:30 PM

—>Tweet this post below! For ADHD Medications: Download complimentary white paper Precise Solutions now, – and get ready for the complete version of ‘The Patient’s Guide’ details to follow. Get Neurotransmitter Details Here

{ 11 comments }

Holistic Reviews At CorePsych

by Dr Charles Parker on January 24, 2010 · 1 comment

Airport Long-Distance Rail Station

Consult Without Travel

Virtual Consult – Heads Up on Two Items
1. Conference Starts Tomorrow Jan 26!
Do consider attending the Holistic Health Virtual Conference, - I look forward to presenting there on Wednesday Jan 27.  I will be very active with feedback at the forum there, and have an excellent slide presentation for you to follow during the program.

We really must stop automatically treating superficial labels in psych, and need to get down to treating real people with evidenced based objectives. Hope you can make it, just hit the Holistic link on the side bar here, – and remember it’s virtual and recorded, you don’t have to be there real time!

2. We Can Talk Privately-
You’re here because you have listened to my podcasts, watched my YouTube videos, read my comprehensive perspective from hundreds of pages of posts and references – so do feel free to set up a time to review your personal matters by phone.

I have been answering a ton of questions on the comments of several posts here at CorePsych Blog [this one with >140 comments], and realize many of the readers here need more time, and more information regarding meds and the issues with meds – and just don’t have someone local to help resolve those next steps. Psych complexity is workable – if it is addressed comprehensively.

If you’re regularly unhappy with you or your child’s progress, have been walking in the darkness for years, and are just plain old frustrated with current inadequate intervention strategies – such as:

- ADHD meds just not working the way they should
- Chronic psych problems that are not resolving
- Refractory, ‘untreatable’ depression
- Unexplained moods and anxiety that won’t quit with multiple complex issues
- Addiction recovery with cravings that sit on your shoulder
- Brain injury interventions – more than just anti-epileptics
- Mixed Medical and Psych challenges, including more extensive testing
- SPECT Brain Imaging Cookie Cutter Results my personal review [or second opinion] – including neurotransmitter specifics

I can then give you targeted feedback if we can connect with your more specific history, laboratory testing, & med trials – and my comprehensive questionnaires that will save us time on the consult.

Phone Consults Are Often Helpful
Helping you decide what-to-do-next, seeking further evidence, is completely reasonable with a phone consult. Millions get on the phone everyday for specific input with medical and psych challenges. I won’t be writing for any medications unless you come to Va Beach, but I can discuss your next investigations. It’s easy, and often just a few visits can add significant, even more useful information.

What I Do
I can order helpful testing, some of which you can do in your own home, often covered by insurance. I can follow your progress with facts. The benefits are simple: more complete questions, more answers, and a concerted effort to give you information you can use with your own trusted medical team there at home. Frequently recommendations include specific neurotransmitter precursors.  We have seen many reduce their medications with these precise interventions, and have treated many without psych meds at all. I do interpret SPECT imaging, reports are customized, comprehensive, about 15-20 pages, and never cookie cutter.

If You Wish To Chat: How
If you are interested in an initial meeting, please drop an email to Caitlin, the CorePsych Administrator.

Thanks, I look forward to our next conversations – and see you at Holistic!
cp

PS: Take a look at this Neuroscience page if you want more information on what we can do together, and would like more references.

—>Tweet this post below! For ADHD Medications: Download complimentary white paper Precise Solutions now, – and get ready for the complete version of ‘The Patient’s Guide’ details to follow. Get Neurotransmitter Details Here

{ 1 comment }

Comprehensive Psych Medication Strategies

January 17, 2010 Brain/Body Evidence

We’re Way Beyond Labels at CorePsych – Psychiatric meds simply won’t work if we don’t understand the entire neurotransmitter process. In this new game of pure neurotransmission, numbers matter.

2 comments Read the full article here →

Holistic Psychiatry is CorePsych

January 4, 2010 Beyond ADHD

Neuroscience evidence changes thinking: This January 26 & 27, just a few weeks away, you will have an opportunity to take a deeper step into that change process: The Holistic Health Virtual Conference: Empowering Whole People – I hope you can join me there.

5 comments Read the full article here →

Sam McGee and Christmas – Family Fun

December 21, 2009 Blog

I had the bright idea that we should celebrate Christmas by reading poetry by the fire, as FDR did with his family. It was a good plan, hatched with two other families, to read poetry every Christmas Eve

4 comments Read the full article here →

Intuniv for ADHD: Avoid Drug Interactions

December 16, 2009 Beyond ADHD

Intuniv Driving And Watching: Possible Interactions Detailed – Regular CorePsych Blog readers already know that we don’t like wrong medication turns. Intuniv dosing is important. Intuniv safety has been carefully explored. Maps do help, but watching where we are going is even better.

13 comments Read the full article here →

Intuniv Answers: ADHD & Addiction Indication

December 15, 2009 Beyond ADHD

Intuniv For ADHD & Substance Abuse – As we move down the early ADHD road of experience with Intuniv some interesting additional indications appear.

0 comments Read the full article here →

Intuniv For ADHD: Dosing Details

November 28, 2009 Autism Spectrum

Intuniv For ADHD Is Guanfacine, But Better and Easier – ADHD treatment evolves: This will be a short note to quickly address the growing comments here at CorePsych Blog on the previous Intuniv post.

55 comments Read the full article here →

Vyvanse diminishes Memory? Watch The Top of The Therapeutic Window

November 14, 2009 Beyond ADHD

Vyvanse can create memory problems and there are several likely explanations, so let’s review. Most importantly, remember these small Vyvanse
challenges do teach us – they point the way to the next logical intervention for the most effective medication dosage strategies.

21 comments Read the full article here →

Neurotransmitters & Psychiatric Medications: The Turkey Shoot Revisited

November 7, 2009 Brain/Body Evidence

Let’s target the symptoms precisely. The approach of Turkey Season serves as a great reminder for what-not-to-do with psychiatric medications and supplements, and how to consider withdrawal from gluten with neurotransmitters.

13 comments Read the full article here →