ADHD Insights: IgG, Immunoglobulins Matter

ADHD Insights: Stuckness, Change and Denial
September 19, 2012
ADHD Insights: Measuring Arsenic
September 21, 2012

ADHD Discoveries: Measurement of IgG and Immunoglobulins Matter

There are other Annapurnas in the lives of men.
Werner Herzog, Author: Annapurna

Everest looms in the distance, and exploring up there requires considerable additional travel effort. Yes, many don't trek there. But some others go without oxygen – several times.

IgG Explorations

IgG findings seem as remote as Everest for ADHD problems

For Mountain Trekking, Maps Matter

If ordinary approaches don't work whilst treating ADHD it becomes necessary to go exploring for the biomedical cause[s]. IgG is one type of several immunoglobulins that can make a serious ADHD recovery difference. If you don't get this one right, the downstream effect is that medication effects become fruitless as neurotransmitter receptors don't work efficiently in the cytokine storms 1 – as cytokines compete for neurotransmitter receptor sites.2

IgG data points require serious, Everest-like, explorations. Think of trekking to Everest for IgGAnnapurna for Trace Elements, and you find yourself traveling on the biomedical mountaineering team.

In distant laboratories, disdained by traditional allergists, reside answers we didn't couldn't trek through before. Yes, we witness these derogatory remarks from our allergy/internal medicine colleagues too often in our offices. The only problem with their negativity: IgG testing works, over 80% of the time. IgG testing is a trip worth making even if you don' have the obvious IgE recognizable symptoms – and even if your highly trained, traditional allergist has a theory that IgG testing won't work. Your allergist focuses on other, somatic matters.

IgG Testing Answers and Measurement Tools – Like And Review:

See this posting from ADHD and Allergies by Anthony Kane MD.

Allergists give allergy shots to treat allergy. The way this works is they give a low level of allergen, which is not enough to elicit an IgE reaction. The dose is slowly increased until eventually the patient can tolerate a significant exposure to the allergen.

This is how it works. The repeated low-level exposure to the allergen induces the body to make a different antibody to the substance. This antibody attaches to the allergen and deactivates it before IgE can cause the allergy reaction. What is this antibody that allergists try to induce to cure their patients of their allergies? You guessed it, IgG. So the very antibody the traditional allergists have been inducing for decades to successfully treat allergies, the food allergy people claim is the antibody guilty of causing allergies.

For a traditional allergist this is nothing short of heresy. IgG has been used for decades to treat allergies successfully.

IgG Measurements

Never overlook the cost-effective Transit Time as a ridiculously easy indicator: Transit Time Details Here

My perspective on the controversy that is not controversial: Allergists focus on traditional medical issues of acuity, life and death [often mitigated by IgE antibodies]. IgE issues do often present as acute and physically painful. Thank goodness allergists can identify and treat those issues!

IgG issues [the Ghost Immunoglobulin] on the other hand, most often arise in the evaluation of chronic, often sub-symptomatic illness that presents as psychosomatic or refractory, untreatable mental problems – that don't respond to traditional psychiatric interventions.

Chronicity is overlooked, acuity moves to the front of the line. For ADHD treatment chronicity and medical subtlety matter.

Take a deeper, biomedical look by traveling to those different IgG mountains.  Measure and treat, see what the world looks like from up there, and form your own conclusions.

In the next CorePsych post visit the base camp for that other mountaintop of Trace Elements and Heavy Metals – the Annapurna of biomedical investigations.

– And if you discover that your or your family is one of the many blown off by traditional medical folk who dispute, deny, and ignore the literature links and testing facilities like Great Plains Labs, give us a call at this link: – and we'll get on this testing right away – no need to debate the data and neuroscience relevance is there, even if some miss this important data.

I can assure you I wouldn't be writing about these matters if they didn't work as important indicators everyday in office.

Dr Charles Parker
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1. Into the eye of the cytokine storm. Microbiol Mol Biol Rev. 2012 Mar ;76(1):16-32. doi: 10.1128/MMBR.05015-11. [linked above]
2. Cytokine-neurotransmitter interactions in the brain De Simoni MG, Imeri L. Biol Signals. 1998 Jan; 7(1):33-44. [linked above]



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  1. Sisson says:

    Hi Doc,

    My GP’s take on IgG testing is the following which to me is a valid argument against IgG – I have a foot in both camps and feel torn between the 2 ideas. Surely Leaky Gut is the root cause of IgG food sensitivities – if you swap your diet wont you merely react to the new diet?

    ..your body will react negatively to any food that escapes into the body without being properly digested first. The more you eat a food, the more likely particles of that food could have snuck through a leaky gut undigested. So the more likely your body has had to make antibodies against that food. If you never ate a food, it would be impossible for you to have antibodies against that food. If you rarely eat a food, you would most likely have few antibodies against that food. Your results are actually totally expected. You would expect that your body would have more antibodies against food you eat more of.”

    • Sisson,
      IgG is not related to amounts and while what you’re saying makes sense logically, the reality is the exposure, period. Variations then occur with the degree of reactivity, not the amount of antigen.

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  5. Jodi says:

    My 9 year old daughter was recently diagnosed with ADD inattentive type. She has a severe peanut allergy and thought that food sensitivities could be the cause of ADD. However, I cannot get her allergist or physician to order an IgG blood test…they find this test to be irrelevant. Any thoughts?

    • Jodi,
      They clearly accept the current, outdated, standard of care. No fault, they with some of the literature. My team and many others are with a different portion of the literature that clearly addresses brain function. Most of the allergy guys focus on live and death, physical manifestations – with chronic illness and disorders brain function becomes much more relevant. Brain function is not, for the most part, their concern, thus the disparity, and missed focus on that available literature.

      Call/write Desiree [CorePsych Patient Care Coordinator], on Mon after 9 EDT at the numbers on this page: and we’ll get her done right away.

    • Jodi,
      I added specific reference links to this article to make it easier for others to review resources.

  6. Melissa Kogut says:

    My son is 13 years old and has tried every medication for behvioral issues. He has been diagnosed with ODD, ADHD< mood disorder. I have had no success with the meds as they werk for maybe a week and then fail. He has extreme history with protein allergies and had a feeding tube for 8 years. He was given neokate for his diet. He did lern to eat again, and thought to gro out of his food/protein allergis but now the behaviroal issues are a huge problem at home and school. I just read about IGE and I am amazed the doctors have not brought this up. Could he be a candidate fot this? How do I get him tested.

  7. Matt says:

    Dr. Parker: Never new that allergists use IGG to treat IGE symptoms. Very interesting. I always learn something new reading your blog. Matt

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