It was a magic moment: this Missouri and Indiana farm boy arrives in LA to speak at the Disney Center. Well…, not at the Disney Center, but darn close, – in Patina [take the tour of the room], the exquisite restaurant right next to it – see the red arrow >
The dining guests dressed impeccably, the physicians in the room: the LA cognoscenti from UCLA, Cedars Sinai and the surround. The evening scene was fresh southern Cally at its resplendent best, and, as you can see from your tour of the room, Patina radiated grand class unlike any restaurant down there in Dexter, MO.
By the way, it was the first time that I entered a dinner meeting room, hooked up my computer to the wall outlet and projected, as you can imagine there near the entrance to the room, my desktop onto a very large plasma screen – no LCD, no shadows with the waiters, – outstanding at that moment. [Now commonplace.]
The Topic: Medications for ADHD
Nope, I won't tell you the specific pharmaceutical company with all of the current ridiculous heat about pharmaceutical dinner meetings, implicit suggestions of mindless drooling docs, and the inferred potential for brainless seduction by pens and post-it notes – why create more problems? Quick take on the attendees: no one was drooling, no one asked for pens, – and the questions were electric, penetrating and without slack. No one was there to party.
The bottom line on the evening: the room was loaded with very smart docs, with deep understandings of psych meds and stimulants, and an abiding interest in growing their deeper understanding of just how this particular ADHD medication worked in clinical practice.
It Works If You Work It
And, for you thoughtful readers out there in the ethers, there was, on that evening, an important discussion that resonates right into this day and this moment. It was a relevant discussion for every medication check, for every doctor and patient interaction across the USA, everyday. The subject in question, introduced by a discerning woman, child psychiatrist from UCLA: tachyphylaxis – does the drug need regular adjusting because the medication over time diminishes in effectiveness?
For videos that explain in more detail: ADHD Meds Dosage: http://bit.ly/dosevids
This particular drug needs less adjustments over time than the average stimulant, a key point for the both the provider and the patient. Medication checks are dollars out of everyone's pocket, create a burden for all, and require more careful medical monitoring than a drug that works consistently over time.
So many psych drugs appear to manifest a roving Therapeutic Window, an unpredictable metabolic pattern that appears to move around and require changing over time – thus resulting in tachyphylaxis.
Metabolism Modifies Efficacy Over Time
At CorePsych the reason we are so vigorously supporting a more evidenced-based approach to core psychiatric issues derives from this all-to-common phenomenon, seen for so many years: roving tachyphylaxis, – created by metabolic challenges and such ubiquitous challenges as immune system dysregulation, and associated with such obvious biomedical problems as changes in transit time.
For videos see this playlist on dosage:ADHD Meds Dosage: http://bit.ly/dosevids I hope you get some use out of this new tachyphylaxis word – and that you use it to dig deeper into the predictable challenges associated with biomedical influences on drug behaviors.
Dr Charles Parker
Author: New ADHD Medication Rules – Brain Science & Common Sense
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