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Thank you Dr.P! That’s the ticket> “We must move beyond ADHD appearances, the superficial description of hyperactivity and inattention, and look at the person with ADHD as a complexity of issues including both biology and psychology. Both mind and body matter.”
In both textbooks I’m studying right now, “Modern Biology” and “Understanding Psychology”, the chapters that explain nuerons are identical somewhat, with drawings, descriptions,etc..”Multitalental Chemical Couries” is quite interesting. The “Modern Biology” is a used book I found at a thrift store, so it’s not so “modern”.. lol. I’m astounded by the new scientific evidenvce that we need to look at here and in your book!
Scott
Scott,
Just reviewing a new anatomy and physiology book with a student, and the illustrations are awesome – the immune system broken down so well into bite size pieces!
Thanks – appreciate your being out there – in the best sense of term…
cp
Open to suggestions……….adhd is treated, but obsessive/compulsive traits and anxiety are not
29 yo, healthy diet, no other health problems (digestion, allergies, sensitivities, etc), aerobic exercise 5+ days/week, good sleep habits, stress management
current — amphetamine 50mg/daily
Other medications tried (some before adhd diagnosis – span over years)
1. Prozac – don’t recall mg, for depression
2. Wellbutrin – don’t recall mg, prescribed to kick start prozac
3. Paxil – 10 mg first night = did not sleep, bad somatic anxiety next day; 2.5 mg next night = only mildly better
4. Abilify – 1 mg first AM = irritable, confused, agitated followed by exhaustion and severe suicidal thoughts
5. Celexa – 10 mg four days in a row AM = 3rd & 4th AM woke with unusual anxiety, 3rd night did not sleep well but slept, 4th night did not sleep at all
Any suggestions? Am aware of no-no for prozac/paxil with amphetamines, and possible interaction with wellbutrin
Seems to me like this is a classic case of needing to balance the serotonin. like the seesaw effect you talked about. NOT depressed or sad much of the time, but I guess it is still an underlying case of depression. In any case. the obsessions/compulsions and anxiety were present before, but made more evident or possibly worse by the amphetamine
Thanks,
Mary
Mary,
Interesting, thoughtful and well informed question – shows your spot on about several issues. If your anxiety it encouraged by AMP and, yes, it does sound like a serotonin problem – then as you say what -to-do.
1. You really should have Neurotransmitter testing to see what is actually going on. If you do have an immune challenge, then IgG testing should follow to remove the offending antigen which could be cranking the serotonin ‘naturally’ or the norepinephrine. The reaction to the Abilify strongly encourages NT testing, and, of course would ask you, not here, about #2 and transit time.
2. On the try it now side, I’ve had considerable luck with Intuniv for the anxiety, OCD type of ADHD that proves refractory to AMP. I am planning a post soon about it, perhaps can get it off this weekend.
3. A new article, also ref. for this post, shows good results mixing AMP with Intuniv – even though Intuniv appears to more directly effect glutamate, I can assure you I have seen many with elevated glutamate levels that show anxiety and considerable irritability.
See what your doc thinks,
cp